Description
D (Vitamin D3 + Vitamin K2) 3 bomb 60000 iu – 4 capsules
This product name suggests a high-dose vitamin supplement containing vitamin D3 and vitamin K2. The exact trade name and formulation could not be verified from official prescribing information, so this description is limited to the verified active ingredients and their established medical context.
Active Ingredient and Medicine Class
Vitamin D3 is cholecalciferol, a fat-soluble vitamin used to prevent or treat vitamin D deficiency and related bone-mineral disorders. It is commonly discussed in regulatory and clinical sources as part of vitamin D supplementation. Vitamin K2 refers to a group of menaquinones; unlike prescription vitamin K1 (phytonadione), K2 is mainly used as a nutritional supplement and is studied for bone-related effects.
Established Medical Uses
Vitamin D supplementation is established for the prevention and treatment of vitamin D deficiency and for supporting normal calcium and phosphate balance. Regulatory sources also describe cholecalciferol as part of products used in bone-health contexts, including osteoporosis-related care when combined with other therapies. Vitamin K is essential for normal blood clotting, and vitamin K supplementation is medically important when deficiency is present. Evidence for routine combined use of vitamin D and K2 for bone health remains limited and is not equivalent to a universally established drug indication.
How It Works
Vitamin D3 is converted in the body to active hormone forms that help the intestine absorb calcium and support bone mineralization. Vitamin K participates in the activation of vitamin K-dependent proteins, including proteins involved in blood coagulation and bone metabolism. In bone research, the combination is studied because vitamin D supports calcium handling while vitamin K supports carboxylation of certain proteins involved in bone matrix regulation.
Important Safety Information
High vitamin D exposure can cause hypercalcemia and related complications, especially with unsupervised high-dose use or in people with conditions that increase vitamin D sensitivity. Vitamin K can interfere with vitamin K antagonist anticoagulants such as warfarin by reducing their anticoagulant effect. Because of this, vitamin K-containing products require particular caution in people using anticoagulants or with a history of clotting disorders.
Possible Side Effects
Vitamin D supplementation may cause gastrointestinal upset and, when excessive, symptoms related to high calcium levels such as weakness, nausea, constipation, confusion, or kidney-related problems. Vitamin K products are usually well tolerated, but clinically important issues are mainly related to interaction with anticoagulant therapy. Serious reactions are uncommon but can occur with overdose, interactions, or underlying disease.
Scientific Evidence
Peer-reviewed evidence suggests that vitamin D deficiency is relevant to bone health, and systematic reviews support cholecalciferol as the standard vitamin D form for correcting deficiency. For vitamin K plus vitamin D, a meta-analysis of randomized trials found improved total bone mineral density and lower undercarboxylated osteocalcin, but the authors also noted limitations and variability across studies. Overall, the clinical benefit of routine combined supplementation remains less certain than the role of correcting proven vitamin D deficiency.
Medical Information Notice
This summary is for educational use only and is based on sources available at the time of review. It does not replace the official patient leaflet, regulatory product information, or individual assessment by a qualified healthcare professional.
Medical Sources
- DailyMed / FDA: FOSAMAX PLUS D (alendronate sodium/cholecalciferol) label. View source
- DailyMed / FDA: PHYTONADIONE tablets prescribing information. View source
- PubMed: Du et al. “The combination effect of vitamin K and vitamin D on human bone quality: a meta-analysis of randomized controlled trials.” Food & Function, 2020. View PubMed article
- PubMed: Sosa Henríquez M, Gómez de Tejada Romero MJ. “Cholecalciferol or Calcifediol in the Management of Vitamin D Deficiency.” Nutrients, 2020. View PubMed article