Description
Thaigra red (Sildenafil) 100 mg
Thaigra red is presented as a sildenafil 100 mg tablet product. Sildenafil is a well-established medicine used for erectile dysfunction in adult men. It is a prescription medicine in many markets and belongs to the phosphodiesterase type 5 (PDE5) inhibitor class.
Active Ingredient and Medicine Class
The verified active ingredient is sildenafil. It is a selective PDE5 inhibitor, a class of medicines that affects the nitric oxide–cGMP pathway involved in smooth muscle relaxation. The 100 mg strength is part of the product identification.
Established Medical Uses
Sildenafil is established for the treatment of erectile dysfunction. Regulatory sources describe its use in adult men who have difficulty getting or maintaining an erection sufficient for satisfactory sexual activity.
How It Works
Sildenafil helps preserve cyclic guanosine monophosphate (cGMP) by inhibiting PDE5. This supports the normal nitric oxide signalling pathway in penile tissue, promoting smooth muscle relaxation and improved blood flow during sexual stimulation.
Important Safety Information
Sildenafil must not be used with nitrates or nitric oxide donors because of the risk of marked hypotension. It is also contraindicated with riociguat and with some potent CYP3A4 inhibitors. Regulatory sources also list hypersensitivity as a contraindication and advise against use in certain patients with recent stroke or myocardial infarction, severe hepatic impairment, or previous non-arteritic anterior ischaemic optic neuropathy. Caution is also warranted in people with cardiovascular disease or low blood pressure. Important interactions include other PDE5 inhibitors and medicines that can lower blood pressure.
Possible Side Effects
Common adverse effects include headache, flushing, dyspepsia, nasal congestion, and dizziness. Visual disturbance can occur. More serious but uncommon reactions include severe hypotension, prolonged or painful erection, sudden vision loss, sudden hearing changes, and serious cardiovascular events reported in post-marketing use.
Scientific Evidence
Clinical reviews and meta-analyses show that sildenafil improves erectile function compared with placebo in many men with erectile dysfunction, with an adverse-effect profile that is generally predictable for the PDE5 inhibitor class. The core mechanism and clinical use are supported by human pharmacology and trial evidence.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet or assessment by a qualified healthcare professional.
Medical Sources
- DailyMed / FDA: SILDENAFIL TABLETS, prescribing information
- Medicines.org.uk (emc): Sildenafil 100 mg film-coated tablets, Summary of Product Characteristics
- Francis SH et al.: “Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction” Expert Opinion on Drug Metabolism & Toxicology, 2005. PubMed
