Description
Vidalista (Tadalafil) 20 mg
Vidalista 20 mg is identified by the supplied product name as a tadalafil tablet. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction. Official prescribing information for tadalafil tablets confirms this active ingredient and therapeutic use.
Active Ingredient and Medicine Class
Active ingredient: tadalafil.
Medicine class: phosphodiesterase type 5 (PDE5) inhibitor. This class increases the effect of nitric oxide-mediated signalling by reducing breakdown of cyclic guanosine monophosphate (cGMP), which helps relax smooth muscle and increase blood flow in erectile tissue.
Established Medical Uses
Regulatory prescribing information for tadalafil tablets lists treatment of erectile dysfunction in adult men as an established indication. Some tadalafil products are also authorised for benign prostatic hyperplasia or combined erectile dysfunction/benign prostatic hyperplasia, but those uses depend on the specific authorised product and region. For this product identification, the verified use is erectile dysfunction.
How It Works
Tadalafil blocks PDE5, an enzyme that breaks down cGMP. During sexual stimulation, this supports the natural nitric oxide pathway, allowing smooth muscle in the penis to relax and blood flow to increase. Clinical reviews describe tadalafil as a long-acting PDE5 inhibitor with an effect window that can extend up to 36 hours after dosing.
Important Safety Information
Tadalafil is contraindicated with any form of organic nitrate because of the risk of marked blood pressure lowering. It is also contraindicated with guanylate cyclase stimulators such as riociguat. Prescribing information advises caution with alpha-blockers, antihypertensives, potent CYP3A4 inhibitors, significant alcohol intake, severe hepatic impairment, and severe renal impairment. It should be used cautiously in people at risk of priapism, and rare vision or hearing problems have been reported with PDE5 inhibitors.
Possible Side Effects
Commonly reported adverse effects include headache, dyspepsia, back pain, muscle pain, flushing, nasal congestion, dizziness, and some visual symptoms. Important rare or serious reactions include prolonged erection or priapism, sudden decrease or loss of vision, and sudden decrease or loss of hearing.
Scientific Evidence
Peer-reviewed reviews and clinical studies support tadalafil’s effectiveness for erectile dysfunction in a broad range of patients, with benefit seen across different severities and causes of erectile dysfunction. Evidence also suggests that its long half-life may offer more flexible timing than shorter-acting PDE5 inhibitors. Meta-analytic data indicate that daily and on-demand tadalafil both improve erectile function, with differences that may be modest depending on the study outcome.
Medical Information Notice
This summary is for educational use only and reflects sources available at the time of review. It does not replace the official patient leaflet, full prescribing information, or assessment by a qualified healthcare professional.
Medical Sources
- DailyMed (U.S. prescribing information): Tadalafil Tablets, full prescribing information. View source
- Eric J H Meuleman et al. “Review of tadalafil in the treatment of erectile dysfunction.” Expert Opinion on Pharmacotherapy (2003). PubMed
