Description
Kamagra (Sildenafil) 100 mg
Kamagra 100 mg is identified by the supplied product name as a sildenafil product. Sildenafil is a prescription phosphodiesterase-5 (PDE5) inhibitor used for erectile dysfunction. The strength here is 100 mg and is included only for product identification.
Active Ingredient and Medicine Class
The verified active ingredient is sildenafil citrate. It belongs to the PDE5 inhibitor class. This class acts on the nitric oxide/cGMP pathway involved in penile blood flow and erectile response.
Established Medical Uses
Sildenafil is established for the treatment of erectile dysfunction. Regulatory prescribing information describes it as indicated to help men with ED achieve and maintain an erection when sexually stimulated. Clinical reviews also describe benefit across a range of ED causes, including vascular and other common underlying conditions.
How It Works
Sildenafil inhibits PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By slowing cGMP breakdown, it supports relaxation of smooth muscle in the corpus cavernosum and improves blood flow during sexual stimulation. It does not itself cause an erection without sexual arousal.
Important Safety Information
Sildenafil must not be used with nitrates or guanylate cyclase stimulators such as riociguat, because of the risk of a marked fall in blood pressure. Caution is also needed with alpha-blockers and other antihypertensive medicines, which may also lower blood pressure. Prescribing information warns against use in people for whom sexual activity is inadvisable because of cardiovascular status.
Important precautions include a history of priapism, non-arteritic anterior ischemic optic neuropathy (NAION), sudden vision loss, sudden hearing loss, and hypersensitivity to sildenafil or tablet components. Exposure may be increased by strong CYP3A4 inhibitors such as ritonavir.
Possible Side Effects
Common adverse effects include headache, flushing, dyspepsia, nasal congestion, abnormal vision, back pain, myalgia, nausea, dizziness, and rash. Serious reactions can include prolonged erection, severe hypotension, sudden vision loss, and sudden hearing loss.
Scientific Evidence
Clinical trials and systematic reviews show sildenafil improves erectile function and the likelihood of successful intercourse compared with placebo. Evidence also supports overall tolerability, while confirming the importance of avoiding contraindicated drug combinations and using caution in patients with cardiovascular risk or interacting medicines.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet, prescribing information, or individual professional assessment.
Medical Sources
- DailyMed / FDA: Sildenafil citrate tablets, prescribing information
- H D Langtry et al., “Sildenafil: a review of its use in erectile dysfunction,” Drugs, 1999. PubMed
