Description
Mebex (Mebendazole) 100 mg
Mebex 100 mg contains mebendazole, an anthelmintic medicine used for certain intestinal worm infections. The product name and strength are consistent with mebendazole tablet formulations described in official prescribing information.
Active Ingredient and Medicine Class
Active ingredient: mebendazole.
Medicine class: benzimidazole anthelmintic.
Mebendazole is a worm medicine that acts against susceptible intestinal nematodes. It is used as an antiparasitic agent rather than an antibiotic or antiviral medicine.
Established Medical Uses
Official prescribing information identifies mebendazole for the treatment of pinworm (Enterobius vermicularis), whipworm (Trichuris trichiura), roundworm (Ascaris lumbricoides), and hookworm infections, including single or mixed infections. PubMed reviews also describe its established role in common intestinal nematode infections.
How It Works
Mebendazole interferes with the worms’ microtubules and reduces their glucose uptake, which depletes their energy supply and leads to death or expulsion from the body.
Important Safety Information
Mebendazole is contraindicated in people with hypersensitivity to the medicine. Official labeling also warns that it is not proven effective for hydatid disease. Clinically important interactions include metronidazole, with reports of serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis when used together. Caution is also warranted with prolonged or higher-than-recommended use because liver enzyme elevations, hepatitis, neutropenia, and agranulocytosis have been reported.
Possible Side Effects
Reported adverse effects include abdominal pain, diarrhea, rash, urticaria, and angioedema. Rare but important reactions include convulsions, liver injury, neutropenia, and agranulocytosis. Some gastrointestinal symptoms may occur when worms are being expelled.
Scientific Evidence
Published clinical literature supports mebendazole as an effective treatment for common soil-transmitted helminths, with strong activity against roundworm, hookworm, and pinworm infections, and useful activity in trichuriasis. Reviews note that efficacy can vary by parasite species, infection burden, and study conditions.
Medical Information Notice
This summary is based on sources available at the time of review and is provided for educational purposes only. It does not replace the official patient leaflet or assessment by a qualified healthcare professional.
Medical Sources
- DailyMed / FDA: Mebendazole Tablets, USP 100 mg — prescribing information. View source
- Urbani C. et al. “Mebendazole in the treatment of helminthiasis.” PubMed, 1976. View PubMed article
