Description
Tastylia (tadalafil) 60 mg
Tastylia is a product name used for a tablet containing tadalafil. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. It is an established medicine for erectile dysfunction, and tadalafil products are also used for some other approved urologic and cardiovascular indications depending on the market and formulation. The product name and strength should be treated as identification details only; the verified active ingredient is tadalafil.
Active Ingredient and Medicine Class
Active ingredient: tadalafil
Medicine class: phosphodiesterase type 5 (PDE5) inhibitor
Tadalafil is a vasodilating medicine that increases blood flow in specific tissues by enhancing the effect of nitric oxide through cyclic guanosine monophosphate (cGMP) signalling.
Established Medical Uses
Official prescribing information for tadalafil tablets includes treatment of erectile dysfunction. In some regulatory labels, tadalafil is also approved for benign prostatic hyperplasia and for combined erectile dysfunction/benign prostatic hyperplasia use. The exact approved uses depend on the product registration in each country.
How It Works
Tadalafil blocks PDE5, an enzyme that breaks down cGMP. By reducing cGMP breakdown, it helps relax smooth muscle and improve blood flow in the penis during sexual stimulation, which can support erection. Its long duration of action is a recognised feature of the medicine.
Important Safety Information
Tadalafil must not be used with nitrates in any form because the combination can cause a dangerous drop in blood pressure. It is also contraindicated in people with a known serious hypersensitivity reaction to tadalafil and with guanylate cyclase stimulators such as riociguat.
Important precautions include cardiovascular disease, low blood pressure, recent serious heart problems, severe liver disease, and significant kidney impairment. Tadalafil can also interact with alpha-blockers, antihypertensives, potent CYP3A4 inhibitors such as ketoconazole or ritonavir, other PDE5 inhibitors, and substantial alcohol intake. Official labeling also warns about prolonged erection, sudden visual loss, and sudden hearing loss.
Possible Side Effects
Common adverse effects include headache, dyspepsia, back pain, muscle pain, nasal congestion, flushing, and limb pain. Less common but serious reactions can include priapism, marked hypotension, allergic reactions, sudden vision loss, and sudden hearing loss.
Scientific Evidence
Peer-reviewed reviews and meta-analyses support tadalafil as an effective PDE5 inhibitor for erectile dysfunction, with benefit lasting up to about 36 hours in many studies. Review literature also notes that headache and dyspepsia are among the most frequent adverse effects, with back pain, nasal congestion, myalgia, and flushing also reported.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet or individual assessment by a qualified healthcare professional.
Medical Sources
- DailyMed / U.S. FDA: Tadalafil Tablets, for oral use — Prescribing Information
- Meuleman EJH et al. “Review of tadalafil in the treatment of erectile dysfunction.” Expert Opinion on Pharmacotherapy (2003). PubMed
