Description
Vidalista (Tadalafil) 80 mg
Vidalista 80 mg is a product name used for tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. Tadalafil is an established medicine for erectile dysfunction in adult men and has also been used in some approved products for benign prostatic hyperplasia and pulmonary arterial hypertension, depending on the formulation and jurisdiction. The 80 mg strength is unusually high compared with commonly authorised tadalafil tablet strengths, so the exact marketed status of this specific product name and strength should be verified against the local product leaflet or regulator listing.
Active Ingredient and Medicine Class
The verified active ingredient is tadalafil. It belongs to the PDE5 inhibitor class. This class works by enhancing the nitric oxide–cGMP pathway in smooth muscle, which helps increase blood flow in the penis during sexual stimulation.
Established Medical Uses
Regulatory sources identify tadalafil as a treatment for erectile dysfunction. In some approved products, tadalafil is also indicated for benign prostatic hyperplasia symptoms, and in separate formulations for pulmonary arterial hypertension. For this product name, the short description supports use for erectile dysfunction, but the specific 80 mg presentation is not confirmed here as a standard authorised strength.
How It Works
Tadalafil inhibits PDE5, the enzyme that breaks down cGMP. By preserving cGMP, it promotes relaxation of smooth muscle and improves blood flow in the corpus cavernosum during sexual stimulation. It does not produce an erection without sexual stimulation.
Important Safety Information
Tadalafil must not be used with nitrates because the combination can cause a dangerous fall in blood pressure. It is also contraindicated with guanylate cyclase stimulators such as riociguat. Important precautions include cardiovascular disease in which sexual activity is inadvisable, a history of non-arteritic anterior ischaemic optic neuropathy, and hypersensitivity to tadalafil. Clinically significant interactions are also noted with alpha-blockers and strong CYP3A4 inhibitors, which can increase the risk of hypotension or tadalafil exposure.
Possible Side Effects
Common adverse effects include headache, dyspepsia, back pain, myalgia, nasal congestion and flushing. Serious but less common reactions can include marked hypotension, visual changes, hearing loss, and prolonged painful erection.
Scientific Evidence
Clinical trials and reviews show tadalafil improves erectile function and is generally effective across a range of patient groups. Evidence also supports a long duration of action and a safety profile consistent with other PDE5 inhibitors, with most adverse effects being mild to moderate.
Medical Information Notice
This summary is based on sources available at the time of review and is intended for educational use only. It does not replace the official patient leaflet, product information, or assessment by a qualified healthcare professional.
Medical Sources
- European Medicines Agency (EMA) — Cialis: EPAR
- DailyMed — Tadalafil tablet
- Rui WB, et al. “Efficacy and safety of tadalafil for erectile dysfunction: an updated review.” Zhonghua Nan Ke Xue. 2009. PubMed
