Description
Varna (Vardenafil) 60 mg
Varna is identified here as a vardenafil-containing medicine. Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction. Official product information for vardenafil medicines describes it as an oral treatment for erectile dysfunction, with clinical evidence supporting improved erectile function in adult men.
Active Ingredient and Medicine Class
The verified active ingredient is vardenafil. It belongs to the PDE5 inhibitor class. This group of medicines is used to improve erectile function by enhancing the normal blood-flow response involved in erection.
Established Medical Uses
Vardenafil is established for the treatment of erectile dysfunction in adult men. Regulatory labelling and clinical reviews support its use for improving erectile function, including in men with common underlying conditions such as diabetes or hypertension.
How It Works
Vardenafil inhibits PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By preserving cGMP, it helps relax smooth muscle and increase blood flow into the penis during sexual stimulation. It does not create an erection by itself; sexual arousal is still required for its effect.
Important Safety Information
Vardenafil must not be used with nitrates or nitric oxide donors because of the risk of marked blood-pressure lowering. It is also contraindicated in certain patients with significant cardiovascular risk, and official labelling warns against use in severe hepatic impairment. Caution is needed with alpha-blockers and other medicines that can lower blood pressure. Important interactions are also described with some strong CYP3A4 inhibitors and other medicines that may increase vardenafil exposure.
Possible Side Effects
Common adverse effects reported with vardenafil include headache, flushing, nasal congestion, indigestion, dizziness, and back pain. More serious but uncommon reactions include prolonged erection, sudden vision loss, and sudden hearing changes. Clinical guidance and product labelling advise prompt medical attention for severe or persistent adverse effects.
Scientific Evidence
Randomised trials and systematic reviews show that vardenafil improves erectile function compared with placebo in men with erectile dysfunction. Published reviews also report benefit across different patient groups, including men with diabetes, hypertension, dyslipidaemia, and post-prostatectomy erectile dysfunction.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet, prescribing information, or assessment by a qualified healthcare professional.
Medical Sources
- FDA / DailyMed – Vardenafil Hydrochloride Tablets, Full Prescribing Information
- European Medicines Agency – Levitra, INN-vardenafil: Scientific Discussion
- Keating GM, Scott LJ. Vardenafil: a review of its use in erectile dysfunction. Drugs. 2003.
