Description
Careforce (Sildenafil) 100 mg
Careforce 100 mg is a sildenafil tablet. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used in the treatment of erectile dysfunction.
Active Ingredient and Medicine Class
The verified active ingredient is sildenafil, usually present as sildenafil citrate in prescribing information. It belongs to the PDE5 inhibitor class of medicines.
Established Medical Uses
Sildenafil is established for the treatment of erectile dysfunction. Regulatory labeling for sildenafil tablets identifies this use, and clinical reviews support its ability to improve erectile function in men with erectile dysfunction of different causes.
How It Works
Sildenafil blocks PDE5, an enzyme involved in breaking down cyclic guanosine monophosphate (cGMP). By preserving cGMP in penile tissue, it helps relax smooth muscle and improves blood flow during sexual stimulation, which can support an erection.
Important Safety Information
Sildenafil is contraindicated with organic nitrates because the combination can cause a marked fall in blood pressure. It is also contraindicated with riociguat. Caution is needed with alpha-blockers and other medicines that lower blood pressure, as additive hypotension may occur. Sildenafil is metabolised mainly by CYP3A4, so strong CYP3A4 inhibitors can increase exposure and may raise the risk of adverse effects. Important precautions in official labeling include cardiovascular risk assessment, low blood pressure, severe liver or kidney impairment, and rare eye-related risks such as non-arteritic anterior ischaemic optic neuropathy.
Possible Side Effects
Common adverse effects include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbance. More serious but less common reactions may include severe hypotension, priapism, sudden vision loss, sudden hearing changes, and allergic reactions.
Scientific Evidence
Peer-reviewed reviews and meta-analyses show that sildenafil is more effective than placebo for improving erectile function and the likelihood of successful intercourse. The benefit has been demonstrated across multiple trial populations, with the main limitations being contraindications, drug interactions, and dose-related adverse effects. Clinical evidence also shows that most adverse effects are transient and that the principal serious interaction concern is with nitrates.
Medical Information Notice
This summary is based on sources available at the time of review and is provided for educational purposes only. It does not replace the official patient leaflet or assessment by a qualified healthcare professional.
Medical Sources
- DailyMed — Sildenafil Tablets, Full Prescribing Information
- Langtry HD et al. — “Sildenafil: a review of its use in erectile dysfunction” — Drugs (1999) — PubMed
