Description
Chocolis (Tadalafil) 20 mg
Chocolis 20 mg is a chewable tadalafil product. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used in the treatment of erectile dysfunction. The product name and strength are used here for identification only; the verified active ingredient is tadalafil.
Active Ingredient and Medicine Class
Active ingredient: tadalafil.
Medicine class: phosphodiesterase type 5 (PDE5) inhibitor.
Tadalafil is a prescription medicine that relaxes smooth muscle and increases blood flow in specific tissues by enhancing the nitric oxide-cGMP pathway.
Established Medical Uses
Regulatory prescribing information for tadalafil tablets identifies erectile dysfunction as an established use. Some tadalafil products are also approved for benign prostatic hyperplasia, and some for both conditions, depending on the specific product and jurisdiction. The exact approved uses for Chocolis should be confirmed from its local product registration.
How It Works
Tadalafil inhibits PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By reducing cGMP breakdown, tadalafil helps maintain the smooth-muscle relaxation needed for increased blood flow during sexual stimulation. Clinical review literature describes tadalafil as having a long duration of action compared with some other PDE5 inhibitors.
Important Safety Information
Tadalafil is contraindicated with nitrates and with guanylate cyclase stimulators because the combination can cause a dangerous drop in blood pressure. Prescribing information also lists hypersensitivity to tadalafil or any component as a contraindication. Caution is advised in people with cardiovascular disease, low blood pressure, recent major heart events, significant liver or kidney impairment, and in those using alpha-blockers, antihypertensives, strong CYP3A4 inhibitors, or other erectile dysfunction therapies.
Important warnings include prolonged erection and rare but serious eye or hearing events. Alcohol may increase the chance of dizziness or low blood pressure.
Possible Side Effects
Common adverse effects include headache, dyspepsia, back pain, muscle pain, flushing, nasal congestion, and pain in the limbs. Less common but serious reactions can include priapism, sudden vision loss, sudden hearing loss, and symptomatic hypotension.
Scientific Evidence
Peer-reviewed reviews and clinical evidence support tadalafil as an effective PDE5 inhibitor for erectile dysfunction, with improvement in erectile function across a range of patient groups. Published reviews also note a relatively long therapeutic window and a safety profile in which headache and dyspepsia are among the most frequent adverse effects.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet, prescribing information, or assessment by a qualified health professional.
Medical Sources
- DailyMed / FDA: Tadalafil Tablets USP Rx Only, Full Prescribing Information
- Eric J H Meuleman, “Review of tadalafil in the treatment of erectile dysfunction,” Expert Opinion on Pharmacotherapy, 2003. PubMed article
