Description
Femalegra (Sildenafil) 100 mg
Femalegra 100 mg is a product name used for a sildenafil-containing medicine. Sildenafil is a prescription phosphodiesterase-5 (PDE5) inhibitor. Official prescribing information for sildenafil products identifies erectile dysfunction as the established indication for this active ingredient.
Active Ingredient and Medicine Class
The verified active ingredient is sildenafil, usually present as sildenafil citrate. It belongs to the PDE5 inhibitor class. This class is used in medicine because it affects a key enzyme involved in smooth-muscle relaxation and blood flow in erectile tissue.
Established Medical Uses
Sildenafil is established for the treatment of erectile dysfunction in men. Prescribing information for sildenafil tablets and Viagra states this indication clearly. Published reviews and trials show that sildenafil can improve erection quality and the ability to complete intercourse in men with erectile dysfunction of different causes.
How It Works
Sildenafil blocks PDE5, which helps preserve cyclic GMP in the penis. During sexual stimulation, this supports relaxation of smooth muscle and increases blood flow to erectile tissue, making an erection more likely. It does not cause an erection on its own without sexual stimulation.
Important Safety Information
Sildenafil is contraindicated with nitrates and nitric oxide donors because the combination can cause a marked drop in blood pressure. It should also not be used with guanylate cyclase stimulators such as riociguat. Prescribing information warns about cardiovascular risk in people for whom sexual activity is inadvisable. Important interactions include alpha-blockers, strong CYP3A4 inhibitors such as ritonavir, ketoconazole, itraconazole and saquinavir, and some other medicines that can raise sildenafil exposure.
Hypersensitivity to sildenafil or any tablet component is also a contraindication. Patients with severe hepatic impairment, severe renal impairment, or older age may have higher sildenafil levels and need special caution in official prescribing information.
Possible Side Effects
Common adverse effects reported with sildenafil include headache, flushing, dyspepsia, nasal congestion and visual disturbance. Less common but important serious reactions can include prolonged erection (priapism), severe hypotension, chest pain associated with sexual activity, and rare hypersensitivity reactions. Systematic review data show that sildenafil increases the risk of several non-serious adverse effects compared with placebo, while serious adverse events were not increased in short-term trials.
Scientific Evidence
Peer-reviewed reviews and meta-analyses consistently find sildenafil effective for erectile dysfunction and generally well tolerated. Trials and pooled analyses report better erectile response than placebo across multiple patient groups, with adverse effects usually mild to moderate and often transient.
Medical Information Notice
This summary is for educational purposes only and is based on sources available at the time of review. It does not replace the official patient leaflet, prescribing information, or assessment by a qualified healthcare professional.
