Description
Valif oral jelly (Sildenafil) 20 mg
Valif oral jelly 20 mg is a sildenafil-containing medicine. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction in adult men. The oral jelly format is a formulation detail; the verified active ingredient is sildenafil.
Active Ingredient and Medicine Class
Active ingredient: sildenafil.
Medicine class: PDE5 inhibitor. This class helps relax smooth muscle and improve blood flow in penile tissue during sexual stimulation.
Established Medical Uses
Sildenafil is established for the treatment of erectile dysfunction. Regulatory sources describe this use as helping men with erectile dysfunction achieve and maintain an erection sufficient for sexual activity when there is sexual stimulation.
How It Works
Sildenafil inhibits PDE5, an enzyme that breaks down cyclic GMP. By preserving cyclic GMP, it supports the normal smooth-muscle relaxation process in the penis and increases blood flow during sexual stimulation.
Important Safety Information
Sildenafil is contraindicated with nitrate medicines because the combination can cause a marked fall in blood pressure. It is also contraindicated with nitric oxide donors. Important caution is needed in people with significant cardiovascular disease, low blood pressure, recent stroke or heart attack, severe liver impairment, and certain inherited eye disorders. Clinically significant interactions are recognised with some alpha-blockers, strong CYP3A4 inhibitors, and other medicines that can affect blood pressure or sildenafil exposure.
Possible Side Effects
Common adverse effects include headache, flushing, indigestion, nasal congestion, dizziness, and visual disturbance. Less common but serious reactions can include prolonged erection, sudden vision loss, sudden hearing decrease or loss, and severe allergic reactions.
Scientific Evidence
Clinical reviews and meta-analyses in men with erectile dysfunction have found sildenafil to be more effective than placebo for improving erections and successful intercourse attempts. The evidence base also supports a predictable safety profile, with most adverse effects being mild to moderate and related to vasodilation.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet or individual assessment by a healthcare professional.
Medical Sources
- DailyMed / FDA — Sildenafil tablets, prescribing information
- European Medicines Agency — Viagra, INN-sildenafil: scientific discussion
- Langtry HD et al. — Sildenafil: a review of its use in erectile dysfunction. Drugs. 1999.
