Description
Cenforce soft (Sildenafil) 100 mg
Cenforce soft is identified by the supplied product name as a sildenafil-containing oral chewable tablet. Sildenafil is a prescription phosphodiesterase type 5 (PDE5) inhibitor used for erectile dysfunction. The verified clinical information below is based on sildenafil prescribing information and peer-reviewed medical literature; the trade name itself was not independently verified.
Active Ingredient and Medicine Class
Active ingredient: sildenafil. Class: phosphodiesterase type 5 (PDE5) inhibitor.
Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific PDE5. It is an oral vasodilating medicine used to improve erectile response during sexual stimulation.
Established Medical Uses
Official U.S. prescribing information identifies sildenafil tablets for the treatment of erectile dysfunction. Clinical reviews and trials show that sildenafil improves the ability to achieve and maintain erections in men with erectile dysfunction of different causes.
How It Works
Sildenafil blocks PDE5, an enzyme that breaks down cGMP in penile tissue. By preserving cGMP, it helps relax smooth muscle and increases blood flow to the corpus cavernosum during sexual stimulation, which supports erection.
Important Safety Information
Sildenafil must not be used with nitrates or nitric oxide donors because of the risk of a marked fall in blood pressure. It should also not be used with riociguat, a guanylate cyclase stimulator. Prescribing information warns that sexual activity can place strain on the heart, so men with cardiovascular disease require careful medical assessment.
Important precautions include a history of low blood pressure, left ventricular outflow obstruction, severe liver disease, severe kidney disease, and anatomical penile deformity or conditions that predispose to priapism. Clinically significant interactions can occur with strong CYP3A4 inhibitors, some alpha-blockers, and other medicines that lower blood pressure.
Possible Side Effects
Common adverse effects include headache, flushing, indigestion, nasal congestion, and visual disturbance. Less common but serious reactions can include prolonged erection, sudden vision loss, sudden hearing loss, allergic reactions, and symptomatic hypotension. Rare cardiovascular events have been reported, usually in people with pre-existing risk factors.
Scientific Evidence
Peer-reviewed reviews and meta-analyses show that sildenafil is more effective than placebo for erectile dysfunction and that its main adverse effects are usually transient and dose-related. Human clinical evidence supports its established role as an oral PDE5 inhibitor for erectile dysfunction.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet, prescribing information, or assessment by a qualified healthcare professional.
Medical Sources
- DailyMed / U.S. prescribing information: Sildenafil tablets, for oral use — Highlights of Prescribing Information
- H D Langtry et al. “Sildenafil: a review of its use in erectile dysfunction.” Drugs (1999). PubMed article
