Description
Fildena (Sildenafil) 100 mg
Fildena 100 mg is a product name associated with sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor. Sildenafil is an established prescription medicine used for erectile dysfunction. Product-name verification can vary by market, but the active ingredient sildenafil is well documented in official prescribing information for sildenafil-containing medicines.
Active Ingredient and Medicine Class
The verified active ingredient is sildenafil. It belongs to the PDE5 inhibitor class. Medicines in this class help increase blood flow in the penis by enhancing the normal nitric oxide–cGMP pathway involved in erection.
Established Medical Uses
Sildenafil is approved for the treatment of erectile dysfunction in adult men. Its established use is to improve erectile function when there is sexual stimulation. It is not a general sexual enhancer and is not used to treat all causes of sexual dysfunction.
How It Works
Sildenafil inhibits PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By limiting cGMP breakdown, it helps smooth muscle in the penile blood vessels relax, allowing increased blood flow during sexual arousal. This mechanism is the basis for its effect in erectile dysfunction.
Important Safety Information
Sildenafil is contraindicated with nitrates or other nitric oxide donors because the combination can cause a dangerous fall in blood pressure. Caution is also required with alpha-blockers and other medicines that may lower blood pressure. Official labeling also warns against use in patients with known hypersensitivity to sildenafil or any tablet component. Cardiovascular status is an important consideration because sexual activity itself may pose risk in some patients with heart disease.
Clinically significant interactions are also reported with strong CYP3A4 inhibitors such as ritonavir, which can increase sildenafil exposure. Sildenafil should not be combined with other PDE5 inhibitors.
Possible Side Effects
Common adverse effects include headache, flushing, dyspepsia, nasal congestion, and changes in vision. More serious but less common reactions can include prolonged erection, sudden blood pressure effects, and rare ocular or cardiovascular events. Safety reviews and prescribing information describe these effects as the main recognised risks in clinical use.
Scientific Evidence
Peer-reviewed reviews and meta-analyses support sildenafil as an effective treatment for erectile dysfunction, with benefits shown across many clinical trials. Published safety reviews report that tolerability is generally acceptable when used as directed, while the known adverse-effect profile remains important for prescribing decisions.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet or individual assessment by a qualified healthcare professional.
Medical Sources
- Official prescribing information: DailyMed, VIAGRA (sildenafil citrate) tablets, for oral use
- Official prescribing information: DailyMed, SILDENAFIL tablets, film coated
- Scientific publication: Francis SH, et al. Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction. Expert Opin Drug Metab Toxicol. 2005.
