Description
Extra super tadarad
Extra super tadarad is presented as a combination product containing tadalafil and dapoxetine. Based on the available prescribing and clinical literature, these ingredients are used respectively for erectile dysfunction and premature ejaculation, although the exact trade name itself could not be verified from an official regulatory source.
Active Ingredient and Medicine Class
Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) developed for premature ejaculation. Both agents are used in male sexual medicine, but they act through different biological pathways.
Established Medical Uses
Tadalafil is an established treatment for erectile dysfunction. Dapoxetine has been studied and used for premature ejaculation, where clinical trials and reviews show improvement in intravaginal ejaculatory latency time and patient-reported control over ejaculation. The combination has been studied in men with both conditions, but the specific fixed-dose product name here was not confirmed in official regulatory labeling.
How It Works
Tadalafil relaxes smooth muscle and increases blood flow to support erection in response to sexual stimulation. Dapoxetine increases serotonin signalling in pathways involved in ejaculation, which can delay ejaculation in men with premature ejaculation. Human studies also suggest that dapoxetine and PDE5 inhibitors can be used together without a major pharmacokinetic interaction, though safety still depends on the individual medicines and coexisting conditions.
Important Safety Information
Tadalafil should not be used with nitrate medicines because of the risk of marked hypotension, and caution is needed with other blood-pressure-lowering medicines and strong CYP3A4 inhibitors. Dapoxetine is contraindicated with monoamine oxidase inhibitors, thioridazine, and serotonin-related medicines that can increase the risk of serotonin syndrome; it also requires caution in patients with a history of fainting or certain psychiatric disorders. Both ingredients may be unsuitable in people with significant cardiovascular disease.
Possible Side Effects
Common adverse effects reported with dapoxetine include nausea, dizziness, headache, diarrhoea, somnolence, and insomnia. Tadalafil is associated with headache, flushing, dyspepsia, nasal congestion, back pain, and muscle pain; rare but important reactions include vision changes and priapism. Combination use may increase the overall burden of side effects.
Scientific Evidence
Randomized clinical trials and meta-analyses show that dapoxetine improves premature ejaculation outcomes versus placebo, and a trial in men already receiving PDE5 inhibitors found added benefit in comorbid premature ejaculation with acceptable short-term tolerability. Smaller clinical studies of tadalafil and dapoxetine together also suggest potential benefit for men with both erectile dysfunction and premature ejaculation, but evidence for any specific commercial combination product remains limited.
Medical Information Notice
This page is an educational summary based on sources available at the time of review and does not replace the official patient leaflet or individual assessment by a qualified health professional.
Medical Sources
- DailyMed / FDA — Tadalafil Tablets, prescribing information. View source
- McMahon CG et al. — “Efficacy and safety of dapoxetine in men with premature ejaculation and concomitant erectile dysfunction treated with a phosphodiesterase type 5 inhibitor: randomized, placebo-controlled, phase III study.” J Sex Med (2013). View PubMed article
